November 2025, Volume 3, Issue 11

Author

Alakhananda Chandranaath, J.J. Lanka Ram and S.K.S. Sutha S. Sellamoni

Abstract

Introduction: Hypergranulation tissue is an excessive proliferation of immature granulation tissue that rises above the wound surface, delaying re-epithelialization. It frequently occurs in post-burn residual raw areas after skin grafting and impedes wound healing. Various management options exist, but there is limited comparative evidence between topical steroid application and compressive dressing. Materials and Methods: A prospective cohort study was conducted at the Department of Burns, Plastic and Reconstructive Surgery, Government Kilpauk Medical College, Chennai, from January to August 2025. Fifty patients with hypergranulation tissue following split-thickness skin grafting were randomly assigned into two groups of twenty-five each. Group A received 0.1% betamethasone with fusidic acid ointment, and Group B received saline compressive dressings. Results: The topical steroid group showed a significantly greater reduction in wound dimensions and pain, with mean raw area decreasing from 34.2 cm2² to 7.2 cm2² compared to 26.3 cm2² to 17.2 cm2² in the compressive group (p < 0.01). Mean healing time was 21.6 ± 7.4 days versus 32.7 ± 10.5 days, and no complications were observed in the steroid group. Conclusion: Short-term topical steroid therapy effectively reduces hypergranulation tissue, accelerates epithelialization, and minimizes hospital visits compared to compressive dressing, with no adverse effects.