November 2025, Volume 3, Issue 11

Author

Deepak Sitaram Laddhad, Vishal Pralhad Gaikwad, Prashant Patil Saurabh Valji Bhanushali and Neha Vijay Nidre

Abstract

This case presents how a patient with multiple endocrine deficiencies having multiple hormonal and metabolic deficiencies eventually led to the diagnosis of Sheehan's syndrome (a rare condition occurring after postpartum haemorrhage during child birth leading to pituitary apoplexy causing Sheehan's syndrome). A 40year old female patient brought to emergency in an unconscious state with GCS score of 5 having severe hypoglycaemia (BSL 26 mg/dl) on presentation with vitals pulse 58 bpm, BP 80/50 mmHg, and SpO? 95%. Patient was immediately shifted to ICU and corrected hypoglycaemia. Despite correction of hypoglycaemia the patient remained unconscious following which further evaluation was done suggested severe hypothyroidism with severe adrenal insufficiencies with hyponatremia with meningitis (CSF studies done). After taking detailed history including obstetric history patient relatives gave history of abortion 6 months ago with massive blood loss (PPH). Patient gradually responded to hormonal therapy. To identify the underlying cause, an MRI with contrast performed which revealed Empty Sella Turcica confirming Sheehan's syndrome.