From: Subject: Write up for DNB Training Programmes Date: Thu, 5 Oct 2006 10:20:41 +0530 MIME-Version: 1.0 Content-Type: text/html; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable Content-Location: file://C:\WINNT\Profiles\Administrator\Desktop\1sep\surgery\Writeup_dnb.htm X-MimeOLE: Produced By Microsoft MimeOLE V5.00.2314.1300 Write up for DNB = Training Programmes

           &n= bsp;           =20 Write up for DNB Training Programmes.

 

  1. Name=20 of the speciality : General = Surgery=20
  2. Name=20 of the topic: Salivary Gland=20 Tumours.=20
  3. Name=20 of the Expert: Prof. Vikram Kate = MS,=20 FRCS (Ed.), FRCS (Glasg.), Ph.D.=20
  4. Name=20 of the Hospital:=20 Jawaharlal Institute of Postgraduate Medical Education & Research=20 (JIPMER), Pondicherry.
5.     =20 Introduction: Salivary = gland tumours=20 are uncommon and represent 2-4% of head and neck neoplasms. The glands = are=20 divided into major and minor salivary gland categories. The major = salivary=20 glands are the parotid, the submandibular, and the sublingual glands. = The minor=20 glands are dispersed throughout the upper aerodigestive tract. Almost = 75% of the=20 salivary gland tumors arise in the parotid gland of which usually 15% = are=20 malignant. 10% of the salivary gland tumours arise in the submandibular = glands=20 and the remaining 15% in the sublingual and minor salivary glands. One = third of=20 the submandibular and more than half of the minor salivary gland tumours = are=20 malignant. Pleomorphic adenoma is the commonest benign tumour of the = salivary=20 glands and mucoepidermoid carcinoma is the commonest malignant tumour.=20

  1. Clinical=20 Features:
    1. History=20

=B7        =20 Mode of=20 onset of the swelling, duration, rate of growth, any ulceration if it = has=20 occurred.

=B7        =20 Exact=20 site where it started differentiates a submandibular from a lower pole = parotid=20 tumour.

=B7        =20 If the=20 swelling increases in size with meals and becomes painful =96 suggestive = of=20 sialolithiasis =96 unlikely to be a tumour.

=B7        =20 History=20 suggestive of facial nerve involvement =96 inability to close the eyes = tightly,=20 food bolus collecting in the cheek, deviation of the angle of the=20 mouth.

=B7        =20 History=20 suggestive of trismus indicates infiltration of malignant tumour in the=20 massetter or pterygoid muscles.

=B7        =20 Any=20 other swellings in the neck if present are suggestive of lymph nodal = metastases.=20

 

    1. Physical=20 examination

=B7     = Examination=20 of the ear lobule. Commonly lifted by parotid = tumours.

=B7     = Physical=20 examination of the swelling =96 site, size, surface, consistency, = mobility and=20 plane of the swelling. Fixity of parotid tumours to massetter / mastoid = /=20 mandible evaluated. Fixity of submandibular or other salivary tumours to = mandible evaluated.

=B7     = Intraoral=20 examination

o   =20 Medial=20 displacement of the lateral oropharyngeal wall and tonsillar bed for = enlargement=20 of deep lobe parotid tumours.

o   =20 Examination=20 of Stensen=92s and Wharton=92s duct for inflammation, discharge of fluid = or stones.=20 Sialadenitis can mimic salivary gland tumour. Bidigital examination of = Stensen=92s=20 duct and palpation of the Wharton=92s duct in the floor of the=20 mouth.

o   =20 Bidigital=20 examination of the parotid gland to evaluate deep lobe enlargement.=20

o   =20 Bidigital=20 examination of the submandibular gland swelling to differentiate from=20 submandibular lymph nodal enlargement. As submandibular swelling = enlarges on=20 either side of mylohyoid muscle, it is palpable bidigitally.=20

=B7     = Examination=20 of the facial, lingual and hypoglossal nerves. Facial involved with = malignant=20 parotid tumour and lingual / hypoglossal with malignant submandibular = gland=20 tumour.

=B7     = Evaluation=20 of trismus if patient has complained in history.

=B7     = Examination=20 of the cervical lymph nodes.

 

  1. Investigations=20

=B7     = Fine=20 needle aspiration cytology is the investigation of choice to confirm=20 diagnosis.

=B7     = CT and=20 MRI are the most useful imaging techniques to evaluate the extent of the = spread=20 of the salivary gland tumours. It also helps in identifying deep lobe=20 enlargement of the parotid tumours.

=B7     = Open=20 and true cut needle biopsy is contraindicated as it leads to tumour = seeding.=20 Open biopsy can be done if the tumour has = ulcerated.

 

  1. Differential=20 diagnosis

=B7     = Enlarge=20 lymph nodes; soft tissue tumours and sialadenitis are common conditions = which=20 can simulate the clinical picture of a salivary gland tumour.

=B7     = DD of=20 salivary gland tumours:

o   =20 Pleomorphic=20 adenoma is the commonest benign tumour.

o   =20 Mucoepidermoid=20 carcinoma is the commonest malignant tumour.

o   =20 Other=20 benign tumours include Warthin=92s tumour (papillary cystadenoma = lymphomatosum)=20 and rarely oncocytoma, lipoma, hemangioma.

o   =20 Other=20 malignant tumours include acinic cell adenocarcinoma, adenoid cystic = carcinoma,=20 squamous cell carcinoma, carcinoma ex-pleomorphic adenoma.

  1. Management:=20
    1. Non-surgical=20 management
    • Surgery=20 is the mainstay of treatment for salivary gland tumours.
    • Radiotherapy=20 (RT) is indicated for the treatment of malignant salivary gland = tumours.=20 Indications for RT in malignancy include=20
          • Extraglandular=20 disease=20
          • Perineural=20 invasion=20
          • Direct=20 invasion of regional structures=20
          • Regional=20 metastases=20
          • High=20 grade malignancy
    • RT=20 may be indicated following excision of recurrent pleomorphic adenoma = to=20 reduce the possibility of further recurrence. =
    1. Surgical=20 management
    • Superficial=20 parotidectomy is the treatment of choice for benign parotid gland = tumours of=20 the superficial lobe. Total parotidectomy is done when deep lobe is=20 involved.=20
    • Excision=20 of the submandibular gland, sublingual or minor salivary gland is = the=20 treatment of choice for benign tumours of these = organs.=20
    • Incisions=20 for the excision of the parotid and submandibular gland = -=20
          • Parotid=20 =96 lazy S incision, modified Blair incision, Sistrunk=92s=20 incision.=20
          • Submandibular=20 =96 Incision is 3-4 cm below and parallel to the lower border = of the=20 horizontal ramus of the mandible. =
    • The=20 nerves at risk during salivary gland surgery =96
          • Facial=20 with parotid gland surgery. Identification aids for facial = nerve on=20 operation table: Conley=92s tragal pointer, posterior belly of = digastric, nerve stimulator, retrograde dissection. 
          • Marginal=20 mandibular, lingual and hypoglossal with submandibular gland=20 surgery.
    • Malignant=20 tumours of the parotid =96
          • When=20 facial nerve is not infiltrated, superficial parotidectomy for = a=20 superficial lobe tumour and total conservative parotidectomy = is=20 performed when the tumour extends into the deep lobe. Facial = nerve is=20 conserved.=20
          • With=20 high grade tumours infiltrating the facial nerve, radical=20 parotidectomy with elective excision of the facial nerve is=20 done.=20
          • If=20 metastases in lymph nodes are present, a modified radical neck = dissection from Level I to Level V is done.=20
    • Malignant=20 tumours of other salivary glands =96=20
          • Radical=20 excision with en-bloc removal of lymph nodes if=20 involved.=20
          • When=20 frank infiltration of the lingual or hypoglossal nerve = present,=20 excision of these nerves is done. =
    • Complications=20 of surgery for salivary glands=20
          • Temporary=20 / permanent facial weakness.=20
          • Frey=92s=20 syndrome.=20
          • Sialocele.=20
          • Marginal=20 mandibular / lingual / hypoglossal nerve injury.=20

***************************